Wednesday, March 2, 2011

Splenectomy related to increase in thrombotic events

In studies of veterans who underwent splenectomies, it is of note that thrombotic events increased with statistical significance.  Some think this is related to the sequestering function of the spleen, but is it not likely that nature in her providence may have an actual function for this organ?

The best guess given the above would be that spleens are essential to removing senescent blood cells from circulation... less jagged edges sticking out to draw a platelet response, less thrombotic events.  Simple.

Can anyone think of an experimental design to test this hypothesis?

In the meantime, stop taking out spleens unnecessarily!

No comments:

Post a Comment